In this article, we will explore the depth of Photobiomodulation, shedding light on its application and presenting the compelling evidence supporting its effectiveness. After that, we will share our unparalleled expertise in providing this innovative therapy at our esteemed facility.
What is Photobiomodulation?
Photobiomodulation, or PBM, as it’s called in the research field, is more than just a trendy treatment. It’s a powerful form of low-level light therapy that holds the key to unlocking the body’s natural healing abilities.
Photo – Light
Bio – Cellular
Modulation – Absorption
Meaning, light absorbs into the cells.
Photons are absorbed by light-absorbing molecules within our cells, known as chromophores, which are responsible for eliciting the therapeutic benefits.
The seemingly miraculous powers of PBM were first unveiled in the 1960s by Endre Mester, and even the researchers at the National Aeronautics and Space Administration (NASA) couldn’t resist harnessing its potential to supercharge the healing processes in space. [1]
The light therapy we use is not just your average treatment – it’s non-invasive, bioregenerative, and packs the rejuvenating power of sunlight without any of those harmful UV effects. Our LightStim+ Devices harness specific red, infrared, and blue light wavelengths that have been scientifically proven to deliver noticeable and long-lasting results. Now you can experience the transformative effects of our therapies when you book a LightStim+ Facial with us.

| Blue | Amber | Light Red | Deep Red | Infrared | Deep Infrared |
|---|---|---|---|---|---|
| 415 nm | 605 nm | 630 nm | 660 nm | 855 nm | 940 nm |
What are the Effects of Photobiomodulation?
Low-powered LED Light Therapy is not just a skincare trend, it’s a scientifically backed powerhouse with a proven track record of health benefits. From fighting aging and banishing acne to providing relief after surgery or intense workouts, this therapy is renowned for its unparalleled healing properties. By zeroing in on cellular inflammation and oxidative stress, while enhancing ATP production and boosting blood circulation, this cutting-edge treatment is a force to be reckoned with. [2]
PBM works in two ways
Increased ATP and Cell Signaling
If you were not aware, ATP (Adenosine Triphosphate) stands at the core of our cellular existence, revered as the “energy currency of life”. It tirelessly produces proteins, enzymes, and growth factors crucial for the wellbeing of collagen, elastin, and the extracellular matrix, granting us the supple, resilient skin we all yearn for. It champions the disposal of cellular waste through lysosomes, influences cell proliferation and demise, and fervently facilitates the transmission of chemical messengers vital for growth, healing, protection, and repair. [3]
As mentioned above, red and infrared light infiltrate the mitochondria, triggering an electron transfer reaction via cytochrome c oxidase. This process enhances the mitochondrial membrane potential and accelerates ATP synthesis, thus stimulating cellular energy production and nitric oxide (NO) production, which for decades has been known as the miracle molecule. [4]
Light Interaction with Cells
Interestingly, the absorption of light by over 200 cell types demonstrates the profound influence light can have on various bodily processes. Neurons, for example, play a crucial role in transmitting signals throughout the nervous system, while keratinocytes are essential for maintaining the skin’s barrier function. The interaction of light with lymphocytes, mast cells, and macrophages underscores its potential impact on the immune response. In addition, the absorption of light by stem cells, neutrophils, and fibroblasts highlights its potential significance in the regulation of tissue regeneration and repair processes.
This extensive interaction with different cell types underscores the intricate relationship between light and the body’s fundamental physiological activities.
How Else is PBM Used?
PBM dominates in applications that truly make an impact:
- Pain, inflammation and edema
- Jaundice (especially in newborns)
- Tissue repair and wound healing
- Oral Mucositis
- Dermatology and Skin Rejuvenation
- Seasonal Affective Disorder
- Radiation-induced Dermatitis
- Lymphedema
But recent groundbreaking studies are revealing its potential for:
- Depression, Anxiety and PTSD
- Traumatic Brain Injury (TBI)
- Cardiovascular Issues and High Blood Pressure
- Alzheimer’s and Parkinson’s Diseases
- As a Pre-Treatment for Exercise Induced Muscle Fatigue
- Post Exercise Muscle Recovery
- Reducing the Appearance of Cellulite
- Stimulating Hair Growth

How We Use LightStim+ in Our Spa
At Hoelle Holistic Health and Spa, we take pride in our ability to harness the wellness potential of Photobiomodulation. In our Holistic Health Spa we PBM in the form of FDA Cleared Low-powered LED Light Therapy Treatments, to unlock a myriad of health benefits.
Skincare Benefits
Anti-Aging
LightStim+ FDA cleared red light therapy is not just your average skincare routine. This powerhouse treatment goes beyond the surface, actively preventing collagen degradation, kickstarting circulation in the lymphatic and vascular systems, and putting a stop to inflammation. By boosting the number of fibroblasts, it works to build dermal proteins for a plumper, firmer look, while also lending a helping hand in enhancing immune function. [5]
Acne
Acne is a pesky skin problem that plagues up to 50 million Americans and 40% of adolescents. Yes, you read that right! A whopping 85% of people have to deal with this at some point in their lifetime. So, what’s causing all this chaos on your skin? Well, there are four main culprits behind this nuisance called acne. [6]
- Inflammation
- Increased sebum production
- Increased keratinization within the hair follicle
- P. acnes bacteria (Propionibacterium) & C. acnes bacteria (Cutibacterium)
We confidently utilize the LightStim+ FDA cleared blue and red light in our spa, effectively annihilating acne-causing bacteria by targeting the porphyrins (chromophores) responsible.
Porphyrins eagerly soak up the invigorating blue wavelengths of light, triggering a powerful chemical reaction to unleash singlet oxygen, the ultimate weapon against acne-causing bacteria. But that’s not all – the red wavelengths work their magic by enhancing blood circulation and supplying oxygen to rejuvenate and mend the follicle, effectively quelling inflammation, redness, and pesky sebaceous (oil) activity.
Other Skin Conditions
In case you’re somehow still not persuaded, numerous other skin conditions have been shown to benefit from light therapy in various studies, including:
- Psoriasis and Ezcema
- Hypertrophic Scars and Keloids
- Burns and Wound Healing
- Reduced UV Damage (Sunburn and Sunspots)
- Vitiligo
Pain Relief
Wound Healing and Tissue Repair
LightStim+ Light Therapy for Pain doesn’t just play around – it gets down to business by regulating and stimulating cells for peak performance. This power-packed therapy aids in healing and repairing damaged tissues, while also taking down painful inflammation and tissue distension. But that’s not all – it also kicks into high gear to release neurotransmitters like serotonin and summon immune cells containing opioids to unleash endorphins that shut down pain at it’s source, offering a “safe, drug-free, and side-effect free way to manage pain of chronic musculoskeletal conditions and fibromyalgia.” [7][8]
Check out the irresistible LightStim+ treatment options at Hoelle Holistic Health and Spa and join the forefront of the health and wellness revolution.
References
[1] Whelan H.T. Proceedings of the AIP Conference Proceedings. Volume 504. AIP Publishing; College Park, MD, USA: 2003. The NASA light-emitting diode medical program—progress in space flight and terrestrial applications; pp. 37–43.
[2] Tafur, J. (2008, August). Low-Intensity Light Therapy: Exploring the Role of Redox Mechanisms. NIH | National Library of Medicine | National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996814/
[3] Dunn, J. (2023, February 13). Physiology, adenosine triphosphate. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK553175/
[4] Moncada, S. (1999, April). Nitric oxide: Discovery and impact on clinical medicine. Journal of the Royal Society of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297136/
[5] Wunsch, A., & Matuschka, K. (2014, February). A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase. Photomedicine and laser surgery. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926176/
[6] Skin conditions by the numbers. American Academy of Dermatology. https://www.aad.org/media/stats-numbers
[7] Gale, G. D., Rothbart, P. J., & Li, Y. (2006). Infrared therapy for chronic low back pain: A randomized, controlled trial. Pain research & management. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2539004/
[8] DE Oliveira, M. F., Johnson, D. S., Demchak, T., Tomazoni, S. S., & Leal-Junior, E. C. (2022, April). Low-intensity laser and led (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions. European journal of physical and rehabilitation medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980499/


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